{"id":5113,"date":"2015-08-06T14:57:34","date_gmt":"2015-08-06T12:57:34","guid":{"rendered":"https:\/\/www.institut-biotherapies.fr\/en\/?p=5113"},"modified":"2015-10-16T14:59:02","modified_gmt":"2015-10-16T12:59:02","slug":"world-premiere-differentiation-of-pluripotent-stem-cells-to-muscle-fiber","status":"publish","type":"post","link":"https:\/\/www.institut-biotherapies.fr\/en\/2015\/08\/06\/world-premiere-differentiation-of-pluripotent-stem-cells-to-muscle-fiber\/","title":{"rendered":"World premiere : differentiation of pluripotent stem cells to muscle fiber"},"content":{"rendered":"<p>This major breakthrough in neuromuscular diseases has just been published August 3, 2015 in Nature Biotechnology.<\/p>\n<table class=\"mceItemTable cke_show_border\" style=\"width: 700px; height: 280px;\" border=\"0\">\n<tbody>\n<tr>\n<td>\n<h5><em>&#8220;<span id=\"result_box\" lang=\"en\"><span class=\"hps\">With our<\/span> <span class=\"hps\">method, which<\/span> <span class=\"hps\">does not require any<\/span> <span class=\"hps\">genetic manipulation<\/span>, we obtain <span class=\"hps\">muscle fibers<\/span> <span class=\"hps\">which contract<\/span>, <span class=\"hps\">but<\/span> <span class=\"hps\">also<\/span> <span class=\"hps\">satellite<\/span> <span class=\"hps\">stem cells<\/span> <span class=\"hps atn\">&#8220;<\/span><\/span><\/em><\/h5>\n<\/td>\n<td>\n<h4><img loading=\"lazy\" decoding=\"async\" class=\"media-element file-media-original\" title=\"Photo Olivier Pourqui\u00e9 IGBMC\" src=\"http:\/\/www.afm-telethon.fr\/sites\/default\/files\/olivierpourquie.jpg\" alt=\"olivier pourqui\u00e9 IGBMC Harvard maladies neuromusculaires recherche\" width=\"227\" height=\"270\" data-fid=\"6926\" data-mce-=\"\" data-cke-saved-src=\"http:\/\/www.afm-telethon.fr\/sites\/default\/files\/olivierpourquie.jpg\" \/><\/h4>\n<\/td>\n<td>\n<h4>Olivier Pourqui\u00e9,<br \/>\nIGBMC and Harvard University<\/h4>\n<p><em>(photo credit : Lola V\u00e9lasquez\/IGBMC)<\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"article-heading\">More information with the original article\u00a0 [ doi:10.1038\/nbt.3297 ] :<\/p>\n<p class=\"article-heading\"><a href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html\">Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy<\/a><\/p>\n<p class=\"article-heading\">Authors :<\/p>\n<ul class=\"authors citation-authors\">\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-1\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-1\"><span class=\"fn\">J\u00e9rome Chal<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-2\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-2\"><span class=\"fn\">Masayuki Oginuma<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-3\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-3\"><span class=\"fn\">Ziad Al Tanoury<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-4\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-4\"><span class=\"fn\">B\u00e9n\u00e9dicte Gobert<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-5\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-5\"><span class=\"fn\">Olga Sumara<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-6\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-6\"><span class=\"fn\">Aurore Hick<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-7\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-7\"><span class=\"fn\">Fanny Bousson<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-8\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-8\"><span class=\"fn\">Yasmine Zidouni<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-9\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-9\"><span class=\"fn\">Caroline Mursch<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-10\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-10\"><span class=\"fn\">Philippe Moncuquet<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-11\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-11\"><span class=\"fn\">Olivier Tassy<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-12\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-12\"><span class=\"fn\">St\u00e9phane Vincent<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-13\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-13\"><span class=\"fn\">Ayako Miyanari<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-14\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-14\"><span class=\"fn\">Agata Bera<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-15\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-15\"><span class=\"fn\">Jean-Marie Garnier<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-16\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-16\"><span class=\"fn\">Getzabel Guevara<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-17\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-17\"><span class=\"fn\">Marie Hestin<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-18\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-18\"><span class=\"fn\">Leif Kennedy<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-19\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-19\"><span class=\"fn\">Shinichiro Hayashi<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-20\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-20\"><span class=\"fn\">Bernadette Drayton<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-21\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-21\"><span class=\"fn\">Thomas Cherrier<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-22\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-22\"><span class=\"fn\">Barbara Gayraud-Morel<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-23\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-23\"><span class=\"fn\">Emanuela Gussoni<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-24\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-24\"><span class=\"fn\">Fr\u00e9d\u00e9ric Relaix<\/span><\/a><span class=\"comma\">,<\/span><\/li>\n<li class=\"vcard no-comma\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-25\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-25\"><span class=\"fn\">Shahragim Tajbakhsh<\/span><\/a><\/li>\n<li class=\"authors-toggle\"><a class=\"name\" href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-26\" data-cke-saved-href=\"http:\/\/www.nature.com\/nbt\/journal\/vaop\/ncurrent\/full\/nbt.3297.html#auth-26\"><span class=\"fn\">Olivier Pourqui\u00e9<\/span><\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>This major breakthrough in neuromuscular diseases has just been published August 3, 2015 in Nature Biotechnology. &#8220;With our method, which does not require any genetic manipulation, we obtain muscle fibers which contract, but also satellite stem cells &#8220; Olivier Pourqui\u00e9, IGBMC and Harvard University (photo credit : Lola V\u00e9lasquez\/IGBMC) More information with the original article\u00a0 &hellip; <a href=\"https:\/\/www.institut-biotherapies.fr\/en\/2015\/08\/06\/world-premiere-differentiation-of-pluripotent-stem-cells-to-muscle-fiber\/\">[Read more]<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,3,8],"tags":[],"class_list":["post-5113","post","type-post","status-publish","format-standard","hentry","category-in-the-media","category-news","category-scientific-publications"],"_links":{"self":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/posts\/5113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/comments?post=5113"}],"version-history":[{"count":1,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/posts\/5113\/revisions"}],"predecessor-version":[{"id":5114,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/posts\/5113\/revisions\/5114"}],"wp:attachment":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/media?parent=5113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/categories?post=5113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/tags?post=5113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}