{"id":5740,"date":"2016-08-23T15:47:57","date_gmt":"2016-08-23T13:47:57","guid":{"rendered":"https:\/\/www.institut-biotherapies.fr\/en\/?page_id=5740"},"modified":"2016-08-23T15:48:08","modified_gmt":"2016-08-23T13:48:08","slug":"mitochondrial-diseases","status":"publish","type":"page","link":"https:\/\/www.institut-biotherapies.fr\/en\/other-diseases\/mitochondrial-diseases\/","title":{"rendered":"Mitochondrial diseases"},"content":{"rendered":"<p style=\"text-align: justify;\">Mitochondrial myopathies represent a range of diseases differing, sometimes a lot, from one another. Among them notably, there are MELAS syndrome (mitochondrial encephalopathy lactic acidosis stroke syndrome), MERRF (myoclonic epilepsy ragged red fibers syndrome), KSS syndrome (Kearns-Sayre syndrome), progressive ophtalmoplegia, ocular\u00a0myopathy&#8230;<\/p>\n<p style=\"text-align: justify;\">All mitochondrial myopathies are diseases of genetic origins.\u00a0Genetics for these diseases are very complex, though more and more understood by researchers studying them. The recent progresses in high throughput sequencing methods enabled, in 2012 alone,\u00a0to discover that UQCRC2, PNPT1, RMD1, LARS, FARS2, BOLA3, MTFMT, EARS2, ACO2, AGK and AFG3L2 genes were involved in these diseases.<\/p>\n<h2 style=\"text-align: justify;\"><\/h2>\n<h2 style=\"text-align: justify;\">Prospective follow-up of a cohort of patients with mitochondrial diseases<\/h2>\n<ul style=\"text-align: justify;\">\n<li><strong>Reference laboratory:\u00a0<\/strong>Institute of Myology<\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><a href=\"http:\/\/www.institut-myologie.org\/en\/recherche-clinique\/essais-en-cours\/mitochondrial-diseases\/\" target=\"_blank\">For further information<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mitochondrial myopathies represent a range of diseases differing, sometimes a lot, from one another. Among them notably, there are MELAS syndrome (mitochondrial encephalopathy lactic acidosis stroke syndrome), MERRF (myoclonic epilepsy ragged red fibers syndrome), KSS syndrome (Kearns-Sayre syndrome), progressive ophtalmoplegia, ocular\u00a0myopathy&#8230; All mitochondrial myopathies are diseases of genetic origins.\u00a0Genetics for these diseases are very complex, &hellip; <a href=\"https:\/\/www.institut-biotherapies.fr\/en\/other-diseases\/mitochondrial-diseases\/\">[Read more]<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":4360,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-5740","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/pages\/5740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/comments?post=5740"}],"version-history":[{"count":2,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/pages\/5740\/revisions"}],"predecessor-version":[{"id":5742,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/pages\/5740\/revisions\/5742"}],"up":[{"embeddable":true,"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/pages\/4360"}],"wp:attachment":[{"href":"https:\/\/www.institut-biotherapies.fr\/en\/wp-json\/wp\/v2\/media?parent=5740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}